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NMI 8739

CAS No. 129024-87-9

NMI 8739 ( Dha-DA conjugate; n-docosahexaenoyl dopamine )

产品货号. M26172 CAS No. 129024-87-9

NMI 8739 is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥770 有现货
10MG ¥1077 有现货
25MG ¥1758 有现货
50MG ¥2576 有现货
100MG ¥3823 有现货
500MG ¥8748 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    NMI 8739
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    NMI 8739 is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.
  • 产品描述
    NMI 8739 is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.(In Vitro):NMI 8739 (2 μM) significantly inhibits IL-6 and CCL-20 release up to 49% and 37%, respectivel. NMI 8739 suppresses the production of PGE2 in a concentration-dependent manner with 25.3%, 75% reduction at doses of 100 nM and 1 μM, respectively.
  • 同义词
    Dha-DA conjugate; n-docosahexaenoyl dopamine
  • 通路
    GPCR/G Protein
  • 靶点
    Dopamine Receptor
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    129024-87-9
  • 分子量
    463.7
  • 分子式
    C30H41NO3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(=O)NCCc1ccc(O)c(O)c1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Jeon JS, Kang HM, Park SY, Choi YW. Comparative study of the photo?protective and anti?melanogenic properties of gomisin D, J and O. Mol Med Rep. 2022 Jan;25(1):8.
产品手册
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